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CS-W001157 4
Total: USD 88.00

H-Ser(Bzl)-OH

  • CAS No. 4726-96-9

  • Cat. No. CS-W008308
  • Purity≥97%
  • MDL No.MFCD00065937

*For research and further manufacturing use only, not for direct human use.

H-Ser(Bzl)-OH|CS-W008308

Structure of 4726-96-9

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General Information

  • CAS No. 4726-96-9
  • Cat. No. CS-W008308
  • Purity ≥97%
  • MDL No. MFCD00065937
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO₃
  • Molecular Weight None
  • Synonym(s) O-Benzyl-L-serine
  • SMILES O=C(O)[C@@H](N)COCC1=CC=CC=C1

Description

H-Ser(Bzl)-OH is a protected serine derivative featuring a benzyl group at the hydroxyl position, offering enhanced stability and ease of handling in peptide synthesis. This residue integrates seamlessly into chain elongation protocols, enabling efficient access to serine-containing sequences under standard conditions.

Application

H-Ser(Bzl)-OH serves as a readily accessible, bench-stable building block for the synthesis of serine-containing peptides and peptidomimetics. The benzyloxycarbonyl (Bzl) group provides robust protection of the hydroxyl function during standard peptide coupling protocols, enabling orthogonal handling with amine-protecting groups. Its compatibility with common deprotection conditions facilitates efficient access to bioactive sequences in medicinal chemistry and synthetic biology workflows.

Synthesis

  • Route1

    References

    • Sajiki, Hironao; Hirota, Kosaku Tetrahedron, 1998 , vol. 54, # 46 p. 13981 - 13996
  • Route2
    • null|null
      4218-63-7
    • ~99%
    • In-stock
      H-Ser(Bzl)-OH|CS-W008308
      4726-96-9

    References

    • Tamamura; Nakamura; Noguchi; Funakoshi; Fujii Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 5 p. 954 - 957
  • Route3

    References

    • Sajiki, Hironao; Hirota, Kosaku Tetrahedron, 1998 , vol. 54, # 46 p. 13981 - 13996

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   0.6151
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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