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Structure of 473596-07-5
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3,5-Dibromo-2-fluoropyridine features a fluorinated pyridine core with bromine substituents at the 3 and 5 positions, enabling selective cross-coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and functional materials, offering enhanced reactivity under palladium catalysis. The combination of fluorine and bromine groups provides orthogonal handling for sequential transformations.
3,5-Dibromo-2-fluoropyridine serves as a versatile building block for the synthesis of substituted pyridines and heterocyclic scaffolds in medicinal chemistry. The ortho-fluoro substituent enables palladium-catalyzed cross-coupling reactions, while the dibromo groups provide complementary sites for further functionalization via Suzuki-Miyaura or Negishi couplings. Its bench-stable nature and predictable reactivity make it well-suited for iterative synthetic sequences in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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