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Structure of 475089-07-7
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4-Bromo-2-(methylthio)aniline features a bromine atom at the para position relative to the aniline nitrogen and a methylthio group in the ortho position, creating a sterically accessible site for coupling reactions. This electron-rich aromatic scaffold enables efficient transition metal-catalyzed transformations, delivering complex heterocycles with high regiocontrol under standard conditions.
4-Bromo-2-(methylthio)aniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient late-stage functionalization via Pd-catalyzed cross-coupling reactions. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the methylthio substituent offers orthogonal reactivity and stability under standard conditions. This compound demonstrates excellent bench stability and compatibility with diverse reaction environments, making it ideal for constructing complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: