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CS-W001157 4
Total: USD 88.00

2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole

  • CAS No. 4760-35-4

  • Cat. No. CS-0599326
  • Purity≥98%
  • MDL No.MFCD00457523

*For research and further manufacturing use only, not for direct human use.

2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole|CS-0599326

Structure of 4760-35-4

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General Information

  • CAS No. 4760-35-4
  • Cat. No. CS-0599326
  • Purity ≥98%
  • MDL No. MFCD00457523
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉ClN₂
  • Molecular Weight 180.63
  • Synonym(s) None
  • SMILES CN1C2=CC=CC=C2N=C1CCl

Description

This chloromethyl-substituted benzimidazole delivers a reactive handle for nucleophilic functionalization. The methyl group enhances stability while the chloromethyl moiety enables efficient coupling under mild conditions. Bench-stable and moisture-tolerant, it integrates readily into synthetic sequences requiring site-specific derivatization.

Application

2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole serves as a versatile synthetic building block for constructing biologically relevant heterocyclic scaffolds. The chloromethyl group enables efficient nucleophilic substitution reactions, facilitating the installation of diverse side chains under mild conditions. Its stability under standard laboratory handling and compatibility with common functional groups make it well-suited for medicinal chemistry campaigns and process-scale synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501

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Computational Chemistry Data

  • TPSA   17.82
  • LogP   2.3121
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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