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CS-W001157 4
Total: USD 88.00

2,6-Dimethoxypyrazine

  • CAS No. 4774-15-6

  • Cat. No. CS-W005486
  • Purity≥98%
  • MDL No.MFCD00955843

*For research and further manufacturing use only, not for direct human use.

2,6-Dimethoxypyrazine|CS-W005486

Structure of 4774-15-6

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General Information

  • CAS No. 4774-15-6
  • Cat. No. CS-W005486
  • Purity ≥98%
  • MDL No. MFCD00955843
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O₂
  • Molecular Weight 140.14
  • Synonym(s) Dimethoxypyrazine
  • SMILES COC1=CN=CC(OC)=N1

Description

L-(-)-Malic acid is used as Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece. It also acts as active ingredient in many sour or tart foods. It is used as synthesizing disincrustant and fluorescent whitening agent. It aids in the production of polyester and alcohol acid resins.

Application

2,6-Dimethoxypyrazine serves as a versatile heterocyclic building block in medicinal chemistry and agrochemical synthesis, offering enhanced solubility and metabolic stability compared to unsubstituted analogs. Its ortho-dimethoxy substitution pattern facilitates electrophilic functionalization and enables coupling reactions under mild conditions. The molecule exhibits good bench stability and is readily purified by flash chromatography, making it well-suited for iterative synthetic workflows and scaffold diversification.

Synthesis

  • Route1
    • In-stock
      2,6-Dichloropyrazine|CS-W010976
      4774-14-5
    • null|null
      124-41-4
    • ~99%
    • In-stock
      2,6-Dimethoxypyrazine|CS-W005486
      4774-15-6

    References

    • Guillou; Jacob; Terrier; Goumont Tetrahedron, 2009 , vol. 65, # 43 p. 8891 - 8895
  • Route2

    References

    • Guillou; Jacob; Terrier; Goumont Tetrahedron, 2009 , vol. 65, # 43 p. 8891 - 8895
  • Route3
    • In-stock
      2,6-Dibromopyrazine|CS-D1575
      23229-25-6
    • null|null
      124-41-4
    • ~%
    • In-stock
      2,6-Dimethoxypyrazine|CS-W005486
      4774-15-6

    References

    • Schaaf; Spoerri Journal of the American Chemical Society, 1949 , vol. 71, p. 2043,2046

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.24
  • LogP   0.4938
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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