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Structure of 478837-18-2
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tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate features a rigid bicyclic scaffold with a hydroxyl group at C3 and a bench-stable tert-butyl ester at C8, enabling direct functionalization in medicinal chemistry. This configuration supports stereoselective transformations and facilitates the synthesis of complex nitrogen-containing heterocycles relevant to CNS-targeted drug discovery.
tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate serves as a versatile bicyclic scaffold for medicinal chemistry, enabling access to constrained nitrogen-containing heterocycles. The pendant hydroxyl group offers a handle for selective derivatization, while the tert-butyl ester facilitates straightforward deprotection under mild acidic conditions. Its stereochemically defined framework provides structural rigidity beneficial in target-oriented synthesis and conformational analysis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: