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Structure of 480424-84-8
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This boronate moiety integrates a difluorinated aryl scaffold with a formyl handle, enabling efficient coupling in Suzuki-Miyaura transformations and facilitating downstream functionalization. The electron-deficient ring enhances reactivity while maintaining bench stability under standard conditions.
(2,3-Difluoro-4-formylphenyl)boronic acid serves as a versatile building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The formyl group provides orthogonal functionality for downstream transformations, including reductive amination or oxime formation, while the difluoro substitution enhances metabolic stability and modulates electronic properties in pharmaceutical intermediates. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring functional group compatibility and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352
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Lot numbers can be found on the outside label of a product: