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Structure of 177583-27-6
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tert-Butyl (trans-4-(aminomethyl)cyclohexyl)carbamate is a bench-stable, moisture-tolerant protecting group for primary amines. This trans-configured cyclohexyl scaffold delivers high stereochemical integrity and facilitates efficient deprotection under mild acidic conditions. The carbamate moiety enables straightforward incorporation into peptide and small-molecule synthesis workflows.
tert-Butyl (trans-4-(aminomethyl)cyclohexyl)carbamate serves as a versatile building block for cyclohexane-based scaffolds, enabling efficient access to bioactive amines via mild deprotection. The trans-configured cyclohexyl ring provides defined stereochemistry, while the tert-butyl carbamate group offers excellent bench stability and orthogonal cleavage under acidic conditions. Its functional group tolerance facilitates downstream transformations in medicinal chemistry campaigns, particularly in the synthesis of GPCR-targeted compounds and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: