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Structure of 481065-92-3
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1-Methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid features a trifluoromethyl group that enhances electron-withdrawing character and metabolic stability. This pyrazole scaffold integrates readily into bioactive molecules, offering improved lipophilicity and target engagement in medicinal chemistry applications. The carboxylic acid moiety enables conjugation or salt formation, facilitating purification and formulation under standard conditions.
1-Methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles via standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid facilitates amide bond formation and conjugation. The molecule exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: