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Structure of 481704-21-6
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(4S)-4-Hydroxy-D-proline methyl ester (hydrochloride) features a stereochemically defined hydroxyl group at the C4 position, enhancing conformational rigidity for peptide backbone modeling. The methyl ester facilitates efficient coupling in solid-phase synthesis, while the hydrochloride salt ensures improved solubility and handling under standard conditions.
(4S)-4-Hydroxy-D-proline methyl ester (hydrochloride) serves as a stereochemically defined building block for the synthesis of hydroxyproline-containing peptides and peptidomimetics. The hydroxyl group at C4 enables facile derivatization and is crucial for stabilizing collagen-like triple helices in bioactive sequences. Its methyl ester functionality offers enhanced solubility and facilitates standard amide coupling protocols, while the hydrochloride salt improves shelf stability and handling. Functions reliably in solid-phase and solution-phase peptide synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: