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Structure of 486-74-8
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4-Quinolinecarboxylic acid was used in the coupling reaction with diamine linker. A 4-quinolinecarboxylic acid analogue, brequinar sodium was used to inhibit dihydroorotate dehydrogenase and the de novo biosynthesis of pyrimidine.
4-Quinolinecarboxylic acid (CAS 486-74-8) drives coupling reactions with diamine linkers to form functionalized architectures in synthetic chemistry. It enables precise molecular scaffolding. Researchers leverage this scaffold to develop potent inhibitors like brequinar sodium, which targets dihydroorotate dehydrogenase and halts pyrimidine biosynthesis in proliferating cells.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: