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Structure of 486422-05-3
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N,N-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide features a boronate ester group integrated with a sulfonamide moiety, enabling efficient cross-coupling under mild conditions. The tetramethyl-substituted dioxaborolane enhances stability and solubility in organic media. This compound serves as a robust building block for constructing functionalized aryl scaffolds in medicinal chemistry and materials science applications.
N,N-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The sulfonamide group provides enhanced solubility and functional group tolerance, while the tetramethyl-substituted dioxaborolane ensures high reactivity and minimal protodeboronation. It facilitates efficient C–C bond formation under mild conditions, enabling streamlined synthesis of biaryl scaffolds and functionalized heterocycles in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: