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Structure of 49674-28-4
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3-Amino-5-(trifluoromethyl)benzonitrile features a trifluoromethyl group that enhances electron-withdrawing character and metabolic stability, while the para-amino functionality enables facile coupling in synthetic routes. This aromatic scaffold integrates readily into pharmaceutical intermediates and functional materials under standard conditions.
3-Amino-5-(trifluoromethyl)benzonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds via cyclization reactions. Its amino and nitrile groups exhibit complementary reactivity, facilitating diverse functionalizations under mild conditions. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, making it valuable for optimizing drug-like properties. Bench-stable and readily purified by recrystallization, it functions effectively in standard coupling and condensation protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: