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Structure of 499-51-4
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4-Hydroxypyridine-2,6-dicarboxylic acid features a rigid pyridine core functionalized with two carboxylic acid groups and a hydroxyl moiety, enabling strong metal chelation and hydrogen bonding. This arrangement supports coordination in supramolecular architectures and catalytic systems, particularly under physiological conditions. The molecule exhibits enhanced solubility and stability in aqueous environments, facilitating use in bioactive compound synthesis and ligand design.
4-Hydroxypyridine-2,6-dicarboxylic acid serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling the construction of bioactive heterocyclic scaffolds. Its orthogonal functional groups—phenolic hydroxyl and two carboxylic acids—facilitate selective derivatization, metal coordination, and solid-phase synthesis. The compound exhibits good bench stability and compatibility with standard purification techniques, making it suitable for use in multi-step syntheses and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: