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CS-W001157 4
Total: USD 88.00

Pyridine-2,6-dicarboxylic acid

  • CAS No. 499-83-2

  • Cat. No. CS-0016012
  • Molecule weight167.12
  • Purity≥95%
  • MDL No.MFCD00006299

*For research and further manufacturing use only, not for direct human use.

Pyridine-2,6-dicarboxylic acid|CS-0016012

Structure of 499-83-2

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General Information

  • CAS No. 499-83-2
  • Cat. No. CS-0016012
  • Purity ≥95%
  • MDL No. MFCD00006299
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅NO₄
  • Molecular Weight 167.12
  • Synonym(s) 2,6-Pyridinedicarboxylic acid
  • SMILES O=C(C1=NC(C(O)=O)=CC=C1)O

Description

.

Application

Pyridine-2,6-dicarboxylic acid serves as a versatile chelating ligand and key building block in the synthesis of heterocyclic scaffolds and metal-organic frameworks. Its two carboxylic acid groups on the pyridine ring enable robust coordination to transition metals, facilitating catalyst design and stabilization of reactive intermediates. The molecule exhibits good bench stability, moderate solubility in polar solvents, and tolerance to common functional groups, enabling straightforward incorporation into multi-step syntheses. It functions effectively in standard coupling reactions and serves as a core scaffold in the development of bioactive molecules and porous materials.

Synthesis

  • Route1
    • null|null
      108-48-5
    • ~93%
    • In-stock
      Pyridine-2,6-dicarboxylic acid|CS-0016012
      499-83-2

    References

    • Dai, Huiling; Xu, Hui Chinese Journal of Chemistry, 2012 , vol. 30, # 2 p. 267 - 272
  • Route2
    • null|null
      83693-15-6
    • ~%
    • In-stock
      Pyridine-2,6-dicarboxylic acid|CS-0016012
      499-83-2
    • In-stock
      Trans-Cinnamic acid|CS-0009610
      140-10-3

    References

    • Fife; Przystas Journal of the American Chemical Society, 1983 , vol. 105, # 6 p. 1638 - 1642
  • Route3

    References

    • Mathes et al. Chemische Berichte, 1953 , vol. 86, p. 584,587

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314-H318-H335
Precautionary Statements : P260-P264-P271-P280-P301+P330+P331-P303+P361+P353-P363-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   87.49
  • LogP   0.478
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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