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Structure of 652-36-8
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2,3,5,6-Tetrafluoroterephthalic acid features a rigid aromatic core with four fluorine substituents positioned to maximize electron-withdrawal and steric control. This configuration enhances stability and solubility in polar aprotic solvents, enabling efficient integration into metal-organic frameworks and conjugated polymers. The carboxylic acid groups facilitate direct coupling reactions under standard conditions.
2,3,5,6-Tetrafluoroterephthalic acid serves as a versatile building block for fluorinated aromatic scaffolds, enabling efficient construction of bioactive heterocycles and pharmaceutical intermediates. Its four fluorine substituents enhance metabolic stability and modulate electronic properties, while the carboxylic acid groups facilitate direct coupling reactions and salt formation. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, including amidation, esterification, and metal-catalyzed cross-couplings.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: