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Structure of 501-89-3
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4-Carboxyphenylacetic acid features a carboxylic acid group directly attached to a phenyl ring, enabling straightforward conjugation and solubility enhancement in aqueous systems. This structure supports integration into bioconjugation workflows, particularly for linker design in antibody-drug conjugates and diagnostic probes. The para-substituted arrangement ensures predictable electronic effects and stability under standard reaction conditions.
4-Carboxyphenylacetic acid serves as a versatile building block for the synthesis of functionalized aromatic compounds and heterocyclic scaffolds. Its dual functionality—carboxylic acid and benzylic position—enables straightforward derivatization via esterification, amidation, or decarboxylative coupling. The molecule exhibits good bench stability and facilitates efficient purification, making it well-suited for medicinal chemistry campaigns and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: