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Structure of 501420-63-9
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2-(3-Bromo-4-fluorophenyl)acetonitrile features a bromo-fluoro-substituted phenyl ring linked to a nitrile-bearing acetyl side chain. This electron-deficient aryl unit enables efficient coupling in cross-coupling reactions, serving as a key building block for pharmaceutical intermediates and functionalized materials under standard conditions.
2-(3-Bromo-4-fluorophenyl)acetonitrile serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its compatible bromo and nitrile functionalities. The molecule exhibits good bench stability and facilitates the construction of biaryl and heterocyclic scaffolds commonly found in pharmaceutical intermediates. Its orthogonal reactivity supports sequential functionalization strategies in complex molecule synthesis.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: