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CS-W001157 4
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2-(1-(tert-Butoxycarbonyl)-4-hydroxypiperidin-4-yl)acetic acid

  • CAS No. 502482-52-2

  • Cat. No. CS-0035998
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(1-(tert-Butoxycarbonyl)-4-hydroxypiperidin-4-yl)acetic acid|CS-0035998

Structure of 502482-52-2

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General Information

  • CAS No. 502482-52-2
  • Cat. No. CS-0035998
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₅
  • Molecular Weight 259.30
  • Synonym(s) 2-[4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid
  • SMILES CC(C)(C)OC(=O)N1CCC(CC1)(CC(=O)O)O

Description

This piperidine-based scaffold features a protected hydroxyl group and a pendant acetic acid, enabling direct conjugation in peptide synthesis. The tert-butoxycarbonyl moiety ensures stability during handling and purification, while the carboxylic acid facilitates efficient coupling reactions under standard conditions.

Application

2-(1-(tert-Butoxycarbonyl)-4-hydroxypiperidin-4-yl)acetic acid serves as a versatile building block for the synthesis of bioactive piperidine derivatives. The protected hydroxypiperidine moiety enables selective functionalization, while the acetic acid handle facilitates conjugation or further derivatization. Its bench-stable Boc group and orthogonal reactivity support efficient peptide and heterocycle assembly in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   87.07
  • LogP   1.2231
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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