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Structure of 614731-04-3
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1-Boc-4-fluoro-4-piperidinecarboxylic acid features a bench-stable Boc-protected piperidine scaffold bearing a fluorine atom at the 4-position, enabling direct incorporation into diverse synthetic sequences. The electron-withdrawing fluorine enhances metabolic stability and modulates basicity, while the protected carboxylic acid facilitates selective derivatization under standard conditions.
1-Boc-4-fluoro-4-piperidinecarboxylic acid serves as a versatile building block for constructing fluorinated piperidine scaffolds prevalent in medicinal chemistry. The Boc group ensures stability and ease of handling, while the pendant carboxylic acid enables straightforward derivatization via amide coupling or reduction. Its fluorine substituent imparts favorable metabolic stability and modulates electronic properties, making it ideal for optimizing bioactive molecules in drug discovery workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: