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CS-W001157 4
Total: USD 88.00

(4-Bromo-2-fluorophenyl)hydrazine hydrochloride

  • CAS No. 502496-24-4

  • Cat. No. CS-W002998
  • Purity≥97%
  • MDL No.MFCD03094166

*For research and further manufacturing use only, not for direct human use.

(4-Bromo-2-fluorophenyl)hydrazine hydrochloride|CS-W002998

Structure of 502496-24-4

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General Information

  • CAS No. 502496-24-4
  • Cat. No. CS-W002998
  • Purity ≥97%
  • MDL No. MFCD03094166
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrClFN₂
  • Molecular Weight 241.49
  • Synonym(s) N'-(5-BROMO-2-FLUORO-PHENYL)-HYDRAZINIUM, CHLORIDE
  • SMILES FC1=CC(Br)=CC=C1NN.Cl

Description

(4-Bromo-2-fluorophenyl)hydrazine hydrochloride features a bromo-fluoro-substituted phenyl ring paired with a hydrazine moiety, enabling direct coupling in heterocyclic synthesis. The hydrochloride salt enhances solubility and stability under standard conditions, facilitating use in transition-metal-catalyzed transformations and medicinal chemistry applications.

Application

(4-Bromo-2-fluorophenyl)hydrazine hydrochloride serves as a versatile building block for constructing bioactive heterocycles, particularly in the synthesis of triazoles and imidazoles via cyclization reactions. Its well-documented stability under standard handling conditions enables reliable use in multi-step sequences, with the bromo and fluoro substituents offering orthogonal reactivity for subsequent cross-coupling or functional group manipulation in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   2.2956
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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