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CS-W001157 4
Total: USD 88.00

(2-Chloro-5-fluorophenyl)hydrazine hydrochloride

  • CAS No. 502496-25-5

  • Cat. No. CS-0030575
  • Purity≥97%
  • MDL No.MFCD03094167
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2-Chloro-5-fluorophenyl)hydrazine hydrochloride|CS-0030575

Structure of 502496-25-5

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Description

This hydrazine derivative features a (2-chloro-5-fluorophenyl) moiety that imparts enhanced reactivity and metabolic stability. It serves as a key intermediate in the synthesis of heterocyclic compounds, particularly in pharmaceuticals targeting kinase pathways. The hydrochloride salt ensures improved solubility and handling under standard bench conditions.

Application

(2-Chloro-5-fluorophenyl)hydrazine hydrochloride serves as a key building block for the synthesis of fluorinated heterocycles and bioactive scaffolds. Its hydrazine functionality enables efficient cyclization reactions, particularly in the formation of imidazoles, triazoles, and other nitrogen-containing ring systems under mild conditions. The molecule exhibits good bench stability and compatibility with common protecting groups, facilitating straightforward purification and integration into multi-step synthetic sequences.

General Information

  • CAS No. 502496-25-5
  • Cat. No. CS-0030575
  • Purity ≥97%
  • MDL No. MFCD03094167
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇Cl₂FN₂
  • Molecular Weight 197.04
  • Synonym(s) 2-Chloro-5-fluorophenylhydrazine hydrochloride
  • SMILES NNC1=CC(F)=CC=C1Cl.[H]Cl

Computational Chemistry Data

  • TPSA   38.05
  • LogP   2.1865
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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