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Structure of 502649-32-3
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1-Boc-3-isopropyl-piperazine is a bench-stable, moisture-tolerant piperazine derivative featuring a bulky isopropyl group at the 3-position and a Boc-protected amine at the 1-position. This combination enhances solubility in organic solvents and simplifies deprotection workflows in synthetic routes. The molecule serves as a key building block for bioactive heterocycles, enabling efficient access to complex scaffolds in medicinal chemistry and drug discovery projects.
1-Boc-3-isopropyl-piperazine serves as a versatile nitrogen-containing building block in medicinal chemistry, enabling efficient access to piperazine-based scaffolds. The Boc group provides stability and orthogonal deprotection under mild acidic conditions, while the isopropyl substituent enhances steric profile and modulates solubility. It functions effectively in amide couplings, reductive aminations, and transition-metal-catalyzed cross-couplings, offering predictable reactivity and ease of purification in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: