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Structure of 503000-87-1
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2-Chloro-6-methoxynicotinic acid features a chlorine substituent at the 2-position and a methoxy group at the 6-position on a nicotinic acid scaffold, delivering enhanced electron-withdrawing character and improved solubility in organic solvents. This combination enables efficient incorporation into pharmaceutical intermediates and bioactive heterocycles under standard coupling conditions.
2-Chloro-6-methoxynicotinic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted nicotinamide and quinoline scaffolds. Its ortho-chloro and meta-methoxy substituents provide orthogonal reactivity for palladium-catalyzed cross-coupling and selective functionalization. The compound exhibits excellent bench stability, facilitates straightforward purification, and functions reliably in standard synthetic workflows for API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: