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Structure of 503538-70-3
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(S)-DIFLUORPHOS is a chiral phosphine ligand featuring two fluorine atoms that enhance electronic modulation and steric control in transition metal catalysis. This bench-stable, moisture-tolerant reagent integrates seamlessly into asymmetric synthesis workflows, enabling high enantioselectivity in cross-coupling and hydrogenation reactions.
(S)-DIFLUORPHOS serves as a highly effective chiral ligand in transition-metal-catalyzed asymmetric transformations, particularly in palladium- and nickel-catalyzed cross-coupling reactions. Its fluorinated phosphine backbone enhances electronic modulation and steric control, enabling high enantioselectivity in C–C bond formation. The ligand exhibits excellent bench stability, ease of handling, and compatibility with diverse functional groups, making it a practical choice for iterative synthesis and process development in pharmaceutical and agrochemical R&D workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: