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Structure of 50534-45-7
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1-Ethylpiperidin-4-amine is a bench-stable, electron-rich amine featuring a primary aliphatic amine group and a sterically accessible piperidine core. This structure enables efficient coupling reactions and facilitates incorporation into functionalized molecular architectures. The ethyl substituent enhances solubility and modulates basicity for tailored reactivity in synthetic applications.
1-Ethylpiperidin-4-amine serves as a versatile nitrogen-containing building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its primary amine functionality facilitates straightforward derivatization, while the piperidine ring provides favorable solubility and metabolic stability. The ethyl substituent enhances lipophilicity and modulates basicity, improving membrane permeability. This compound exhibits bench stability and compatibility with standard coupling and functional group interconversion protocols, making it a practical choice for lead optimization and API synthesis.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: