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Structure of 50591-22-5
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1-Methyl-1H-benzo[d]imidazol-5-ol features a fused heterocyclic core with a methylated imidazole ring and a phenolic hydroxyl group, delivering enhanced solubility and stability under standard conditions. This scaffold integrates readily into bioactive molecule design, particularly in kinase inhibitor development and fluorescent probe engineering.
1-Methyl-1H-benzo[d]imidazol-5-ol serves as a versatile heterocyclic building block in medicinal chemistry, offering a stable, bench-compatible scaffold for derivatization at the C5 position. Its phenolic hydroxyl group enables facile functionalization via etherification, esterification, or transition-metal-catalyzed coupling reactions. The methylated imidazole core provides enhanced metabolic stability and favorable solubility profiles, making it suitable for the synthesis of bioactive compounds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: