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Structure of 50593-91-4
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Methyl 5-bromo-2-(methylthio)pyrimidine-4-carboxylate features a brominated pyrimidine core with a methylthio group at C2 and a methyl ester at C4, enabling direct functionalization in cross-coupling and heterocyclic synthesis. This bench-stable reagent integrates readily into advanced building blocks for pharmaceutical and agrochemical development.
Methyl 5-bromo-2-(methylthio)pyrimidine-4-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions at the C5 bromine site. The methylthio group at C2 provides orthogonal reactivity for selective transformations, while the ester functionality supports further derivatization. This compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthesis of pyrimidine-based scaffolds relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: