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Structure of 50606-58-1
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1-Benzylpiperidin-3-one hydrochloride features a rigid, electron-deficient piperidinone core with a benzyl group at the nitrogen, enhancing metabolic stability and membrane permeability. This bench-stable, moisture-tolerant compound integrates readily into medicinal chemistry libraries for CNS-targeted drug discovery, serving as a key scaffold in kinase inhibitor and receptor modulator development.
1-Benzylpiperidin-3-one hydrochloride serves as a versatile scaffold in medicinal chemistry, enabling efficient access to piperidine-based pharmacophores. Its bench-stable crystalline form facilitates handling and purification, while the ketone functionality supports diverse transformations including reductive amination, nucleophilic addition, and cyclization reactions. The benzyl group enhances lipophilicity and provides a handle for further derivatization, making it a practical building block for API development and target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: