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Structure of 50741-37-2
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This tetrahydroquinoline derivative features a rigid, electron-rich heterocyclic core paired with a terminal nitrile group. The scaffold integrates seamlessly into medicinal chemistry campaigns, offering enhanced metabolic stability and favorable membrane permeability. Its bench-stable nature enables straightforward handling in synthetic workflows.
1,2,3,4-Tetrahydroquinoline-8-carbonitrile serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its nitrile group offers high functional group tolerance and facilitates downstream transformations such as amidation or hydrolysis. The saturated quinoline core provides structural rigidity and favorable pharmacophore properties, while the compound exhibits excellent bench stability and ease of purification—ideal for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: