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Structure of 3373-00-0
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6-Hydroxy-1,2,3,4-tetrahydroquinoline features a hydroxyl group at the 6-position of a saturated quinoline core, enhancing solubility and enabling direct functionalization. This bench-stable scaffold integrates readily into bioactive molecule synthesis, offering a polar handle for conjugation while maintaining favorable metabolic profile and structural rigidity in drug discovery campaigns.
6-Hydroxy-1,2,3,4-tetrahydroquinoline serves as a versatile scaffold for medicinal chemistry and natural product synthesis, offering a readily accessible phenolic functionality within a saturated quinoline core. Its hydroxyl group enables direct derivatization via etherification, esterification, or metal-catalyzed coupling reactions, while the nitrogen atom supports selective N-functionalization. The compound exhibits good bench stability and facilitates efficient purification by standard chromatographic methods, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: