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Structure of 51-44-5
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3,4-Dichlorobenzoic acid was employed as internal standard during the multiresidue analysis of pharmaceuticals and personal care products by ultra performance liquid chromatography-positive/negative electrospray tandem mass spectrometry. It was used to study the metabolic fate of 4-chloro-3,5-dinitrobenzoic acid.
3,4-Dichlorobenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient derivatization via esterification, amide formation, and Suzuki-Miyaura coupling. Its ortho-dichloro substitution pattern enhances metabolic stability and modulates electronic properties, while the carboxylic acid group offers straightforward purification and functionalization. Bench-stable and readily available, it functions reliably in standard synthetic workflows requiring halogenated aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: