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Structure of 51114-68-2
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3-Chloro-2-methoxyaniline features a chlorinated aromatic ring paired with a methoxy group in the ortho position, delivering enhanced electron density and improved solubility in polar organic solvents. This configuration supports efficient coupling reactions in pharmaceutical synthesis and enables selective functionalization under mild conditions.
3-Chloro-2-methoxyaniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted heterocycles via electrophilic aromatic substitution or Suzuki-Miyaura coupling. The ortho-methoxy group enhances nucleophilicity at the adjacent position, while the chloro substituent provides a reliable handle for palladium-catalyzed transformations. Bench-stable and readily purified by column chromatography, it functions effectively in multi-step syntheses requiring functional group compatibility and predictable reactivity patterns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: