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Structure of 51145-57-4
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Ethyl 2-((dimethylamino)methylene)-3-oxobutanoate features a conjugated enone system flanked by a dimethylamino group, enabling efficient Michael addition reactions. This electron-rich enone integrates readily into complex heterocyclic frameworks under mild conditions, offering high regioselectivity in C–C bond formation. The molecule’s bench-stable nature and solubility in common organic solvents streamline handling during synthetic sequences.
Ethyl 2-((dimethylamino)methylene)-3-oxobutanoate serves as a versatile synthetic building block in heterocycle construction, enabling efficient access to substituted pyrroles and other nitrogen-containing scaffolds via condensation and cyclization protocols. Its enolizable β-ketoester functionality facilitates aldol-type reactions and Michael additions, while the dimethylamino group enhances electrophilic activation. The compound exhibits good bench stability and is readily purified by distillation or chromatography, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: