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CS-W001157 4
Total: USD 88.00

3-Amino-4-iodobenzoic acid

  • CAS No. 51411-81-5

  • Cat. No. CS-0041328
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Amino-4-iodobenzoic acid|CS-0041328

Structure of 51411-81-5

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Description

3-Amino-4-iodobenzoic acid features a carboxylic acid group flanked by an amino substituent and a reactive iodine atom at the para position relative to the amine. This arrangement enables direct coupling in cross-coupling reactions, facilitating efficient access to functionalized aromatic scaffolds. The molecule exhibits enhanced solubility in polar solvents and stability under standard bench conditions.

Application

3-Amino-4-iodobenzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its orthogonal functionality—amine, iodine, and carboxylic acid—enables sequential derivatization via Suzuki-Miyaura coupling, amidation, or electrophilic substitution. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

General Information

  • CAS No. 51411-81-5
  • Cat. No. CS-0041328
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆INO₂
  • Molecular Weight 263.03
  • Synonym(s) 3-Amino-4-Iodo Benzoic Acid 4-Iodo-3-Amino Benzoic Acid
  • SMILES NC1=C(I)C=CC(=C1)C(O)=O

Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.5716
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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