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Structure of 514798-03-9
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3-Chloro-5-fluoropyridine-4-carboxylic acid features a pyridine core functionalized with chlorine, fluorine, and carboxylic acid groups at strategic positions. This electron-deficient heterocycle enables efficient coupling reactions in medicinal chemistry and agrochemical synthesis. The carboxylic acid moiety provides a handle for derivatization, while the halogen substituents facilitate cross-coupling transformations. Bench-stable and moisture-tolerant, it serves as a key building block for bioactive molecules.
3-Chloro-5-fluoropyridine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive heterocycles via standard coupling reactions. Its orthogonal halogenation pattern facilitates selective functionalization, while the carboxylic acid group supports facile derivatization through amide, ester, or acyl transfer reactions. Bench-stable and readily purified by recrystallization, it functions effectively in both small-molecule synthesis and API intermediate development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501
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Lot numbers can be found on the outside label of a product: