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Azido-PEG5-amine

  • CAS No. 516493-93-9

  • Cat. No. CS-0114401
  • Molecule weight306.36
  • Purity≥97%
  • MDL No.MFCD16619318

*For research and further manufacturing use only, not for direct human use.

Azido-PEG5-amine|CS-0114401

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General Information

  • CAS No. 516493-93-9
  • Cat. No. CS-0114401
  • Purity ≥97%
  • MDL No. MFCD16619318
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₆N₄O₅
  • Molecular Weight 306.36
  • Synonym(s) 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine
  • SMILES NCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Description

Azido-PEG5-amine features a terminal azide group linked via a five-ethylene glycol spacer to a primary amine, enabling efficient copper-free click chemistry. This bifunctional construct combines excellent solubility with stable handling, facilitating site-specific conjugation in bioorthogonal labeling and polymer functionalization workflows.

Application

Azido-PEG5-amine serves as a versatile bifunctional linker for bioconjugation and polymer chemistry, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) due to its terminal azide and amine groups. The five-ethylene glycol units provide excellent solubility and stability in aqueous and organic media, while the primary amine facilitates conjugation via amide or imine formation. Its bench-stable, well-characterized structure supports reliable use in peptide labeling, surface functionalization, and drug delivery system development.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   120.93
  • LogP   0.3384
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   17

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