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Structure of 51746-87-3
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4-(1H-Imidazol-5-yl)pyridine features a rigid, planar architecture combining a pyridine ring with an imidazole moiety, enabling strong π-stacking and coordination versatility. This bifunctional scaffold integrates seamlessly into metal-ligand frameworks and organic electronic materials, offering enhanced stability under standard conditions.
4-(1H-Imidazol-5-yl)pyridine serves as a versatile heterocyclic building block in medicinal chemistry and catalysis. Its dual nitrogen-rich core enables strong coordination to transition metals and facilitates hydrogen bonding in target binding. The molecule exhibits excellent bench stability, moderate solubility in common organic solvents, and tolerates a range of functional groups during synthesis. It functions effectively as a ligand in cross-coupling reactions and as a scaffold for developing bioactive compounds, particularly in kinase inhibitor and metal complex design.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: