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Structure of 517874-21-4
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This boronate ester integrates a dihydrobenzodioxin moiety with a tetramethyl-1,3,2-dioxaborolane unit, offering enhanced stability and compatibility in Suzuki-Miyaura cross-coupling reactions. The electron-rich aryl group enables efficient palladium-catalyzed bond formation under mild conditions, while the steric protection around boron minimizes protodeboronation. Ideal for constructing complex biaryl architectures in medicinal chemistry and materials synthesis.
2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a robust boronate building block for Suzuki-Miyaura cross-coupling reactions. Its dihydrobenzodioxin moiety provides structural rigidity and metabolic stability, while the tetramethyl-substituted dioxaborolane enhances bench stability and functional group tolerance. This reagent facilitates efficient C–C bond formation under mild conditions, enabling rapid access to biaryl architectures common in pharmaceutical and agrochemical synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: