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Structure of 518044-42-3
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Mal-PEG6-acid features a maleimide group conjugated to a six-ethylene glycol unit, terminating in a carboxylic acid. This structure enables site-specific bioconjugation via thiol-Michael addition, while the PEG spacer enhances solubility and reduces aggregation. The terminal acid facilitates further coupling reactions under standard amine-functionalization conditions.
Mal-PEG6-acid serves as a versatile bifunctional linker for conjugation and bioconjugation applications. The maleimide group enables site-specific, thioether bond formation with cysteine residues under physiological conditions, while the terminal carboxylic acid facilitates amide coupling or further derivatization. Its PEG6 spacer provides enhanced solubility and reduced steric hindrance, improving reactivity and stability in aqueous environments. Ideal for antibody-drug conjugate synthesis and peptide modification workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: