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Structure of 518070-19-4
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3-Fluoro-5-methylbenzoic acid features a strategically positioned fluorine atom and methyl group on the aromatic ring, enhancing electron-withdrawing character and metabolic stability. This substitution pattern supports direct incorporation into bioactive scaffolds, enabling efficient derivatization in medicinal chemistry campaigns under standard conditions.
3-Fluoro-5-methylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive compounds through standard esterification, amide coupling, and Suzuki-Miyaura cross-coupling reactions. Its ortho-fluoro and meta-methyl substituents provide predictable electronic modulation and enhanced metabolic stability, while its bench-stable solid form facilitates straightforward handling and purification in routine synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: