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Structure of 52112-66-0
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2-Amino-6-bromobenzoxazole is a heterocyclic aromatic compound featuring an amino group and a bromine atom at the 2- and 6-positions, respectively. This combination imparts enhanced reactivity for cross-coupling applications while maintaining stability under standard conditions. The electron-rich amine facilitates nucleophilic substitution, and the bromine serves as a reliable coupling handle in palladium-catalyzed transformations.
2-Amino-6-bromobenzoxazole serves as a versatile building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. The bromo group facilitates reliable Suzuki, Stille, or Negishi coupling, while the amino functionality supports further derivatization through acylation or electrophilic substitution. Its bench-stable crystalline form and compatibility with standard synthetic workflows make it well-suited for iterative library synthesis and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: