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CS-W001157 4
Total: USD 88.00

3-Hydroxy-4-aminopyridine

  • CAS No. 52334-53-9

  • Cat. No. CS-W008188
  • Purity≥98%
  • MDL No.MFCD01941262

*For research and further manufacturing use only, not for direct human use.

3-Hydroxy-4-aminopyridine|CS-W008188

Structure of 52334-53-9

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General Information

  • CAS No. 52334-53-9
  • Cat. No. CS-W008188
  • Purity ≥98%
  • MDL No. MFCD01941262
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆N₂O
  • Molecular Weight 110.11
  • Synonym(s) None
  • SMILES OC1=C(N)C=CN=C1

Description

3-Hydroxy-4-aminopyridine features a strategically positioned hydroxyl group adjacent to an amino functionality on a pyridine scaffold, enabling strong hydrogen bonding and enhanced solubility. This combination supports efficient integration into pharmaceutical intermediates and bioactive molecule scaffolds, particularly in kinase inhibitor and nucleoside analog development.

Synthesis

  • Route1
    • N-(3-Hydroxypyridin-4-yl)pivalamide|CS-0082359
      169205-93-0
    • ~99%
    • In-stock
      3-Hydroxy-4-aminopyridine|CS-W008188
      52334-53-9

    References

    • Ahn, Sung Oh; Park, Chan Hee; Im, Jun Hwan; Lee, Soon Ok; Lee, Kyoung June; Cho, Seong Wook; Ko, Kwang Seok; Han, Sun Young; Lee, Won Il Patent: US2011/28467 A1, 2011 ; Location in patent: Page/Page column 16 ; US 20110028467 A1
  • Route2

    References

    • C.D. Searle and Co. Patent: US5652363 A1, 1997 ;
  • Route3
    • null|null
      142222-73-9
    • ~88%
    • In-stock
      3-Hydroxy-4-aminopyridine|CS-W008188
      52334-53-9

    References

    • Shutske; Tomer; Kapples; Hrib; Jurcak; Bores; Huger; Petko; Smith Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 4 p. 380 - 385

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.14
  • LogP   0.3694
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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