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Structure of 5239-82-7
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2-Cyclopropylacetic acid features a cyclopropyl ring directly attached to the alpha carbon, imparting unique steric and electronic characteristics. This configuration enhances metabolic stability while maintaining favorable solubility for use in medicinal chemistry applications. The carboxylic acid functionality enables straightforward derivatization, facilitating incorporation into bioactive molecules.
2-Cyclopropylacetic acid serves as a valuable building block in medicinal chemistry, enabling the introduction of a rigid, lipophilic cyclopropyl moiety adjacent to a carboxylic acid functional group. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient peptide and small-molecule synthesis. The cyclopropyl ring enhances metabolic stability and modulates physicochemical properties, making it particularly useful in optimizing drug candidates for target engagement and pharmacokinetics.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: