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Structure of 5267-07-2
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5-Pyrimidineacetic acid is a bench-stable, moisture-tolerant heterocyclic carboxylic acid featuring a pyrimidine core with a pendant acetic acid group. This scaffold integrates readily into medicinal chemistry libraries, serving as a key building block for kinase inhibitors and nucleoside analogs due to its favorable solubility and metabolic stability under standard conditions.
5-Pyrimidineacetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrimidine-based bioactive molecules. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the pyrimidine ring provides a stable heterocyclic core for structure-activity studies. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for use in multi-step synthetic sequences targeting kinase inhibitors and antiviral agents.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: