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CS-W001157 4
Total: USD 88.00

5-Pyrimidineacetic acid

  • CAS No. 5267-07-2

  • Cat. No. CS-W004899
  • Molecule weight138.12
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Pyrimidineacetic acid|CS-W004899

Structure of 5267-07-2

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General Information

  • CAS No. 5267-07-2
  • Cat. No. CS-W004899
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆N₂O₂
  • Molecular Weight 138.12
  • Synonym(s) pyrimidin-5-ylacetic acid
  • SMILES N1=CN=CC(=C1)CC(=O)O

Description

5-Pyrimidineacetic acid is a bench-stable, moisture-tolerant heterocyclic carboxylic acid featuring a pyrimidine core with a pendant acetic acid group. This scaffold integrates readily into medicinal chemistry libraries, serving as a key building block for kinase inhibitors and nucleoside analogs due to its favorable solubility and metabolic stability under standard conditions.

Application

5-Pyrimidineacetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrimidine-based bioactive molecules. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the pyrimidine ring provides a stable heterocyclic core for structure-activity studies. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for use in multi-step synthetic sequences targeting kinase inhibitors and antiviral agents.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.08
  • LogP   0.1037
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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