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CS-W001157 4
Total: USD 88.00

5-Pyrimidineacetic acid

  • CAS No. 5267-07-2

  • Cat. No. CS-W004899
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Pyrimidineacetic acid|CS-W004899

Structure of 5267-07-2

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Description

5-Pyrimidineacetic acid is a bench-stable, moisture-tolerant heterocyclic carboxylic acid featuring a pyrimidine core with a pendant acetic acid group. This scaffold integrates readily into medicinal chemistry libraries, serving as a key building block for kinase inhibitors and nucleoside analogs due to its favorable solubility and metabolic stability under standard conditions.

Application

5-Pyrimidineacetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrimidine-based bioactive molecules. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the pyrimidine ring provides a stable heterocyclic core for structure-activity studies. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for use in multi-step synthetic sequences targeting kinase inhibitors and antiviral agents.

General Information

  • CAS No. 5267-07-2
  • Cat. No. CS-W004899
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆N₂O₂
  • Molecular Weight 138.12
  • Synonym(s) pyrimidin-5-ylacetic acid
  • SMILES N1=CN=CC(=C1)CC(=O)O

Computational Chemistry Data

  • TPSA   63.08
  • LogP   0.1037
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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