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CS-W001157 4
Total: USD 88.00

D-Penylalaninol

  • CAS No. 5267-64-1

  • Cat. No. CS-W018114
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD00064298

*For research and further manufacturing use only, not for direct human use.

D-Penylalaninol|CS-W018114

Structure of 5267-64-1

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General Information

  • CAS No. 5267-64-1
  • Cat. No. CS-W018114
  • Purity ≥97%
  • MDL No. MFCD00064298
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO
  • Molecular Weight None
  • Synonym(s) D-Phenylalaninol
  • SMILES OC[C@H](N)CC1=CC=CC=C1

Description

D-Penylalaninol features a chiral benzylic alcohol scaffold derived from D-phenylalanine, offering enhanced solubility and metabolic stability compared to parent amino acids. This hydroxylated analog integrates readily into peptide architectures, serving as a conformationally constrained residue that modulates backbone flexibility. Its aromatic side chain supports π–π interactions in target binding domains. The molecule exhibits bench-stable handling characteristics under standard conditions.

Application

D-Penylalaninol serves as a valuable chiral building block in peptide synthesis and medicinal chemistry, offering a stable benzyl side chain with a primary alcohol functionality. Its well-defined stereochemistry enables stereoselective transformations, while the hydroxyl group facilitates derivatization or incorporation into bioactive scaffolds. The compound exhibits good bench stability and compatibility with standard protecting group strategies, making it suitable for multi-step synthetic sequences in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.5487
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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