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Structure of 5272-36-6
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3-(Trimethylsilyl)-2-propyn-1-ol features a terminal alkyne bearing a trimethylsilyl-protected hydroxyl group, enabling stable storage and selective deprotection under mild conditions. This functionality facilitates efficient coupling in Sonogashira reactions and enables the installation of protected alcohol handles in complex molecule synthesis.
3-(Trimethylsilyl)-2-propyn-1-ol serves as a versatile building block in synthetic organic chemistry, enabling efficient Sonogashira coupling reactions and acting as a protected alkyne handle. Its trimethylsilyl group provides excellent stability and facilitates selective deprotection under mild conditions. The molecule exhibits favorable bench stability, ease of handling, and compatibility with diverse functional groups, making it well-suited for complex molecule assembly in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H227-H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: