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Structure of 52916-16-2
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This tetrahydropyran derivative features a sterically hindered, bench-stable carboxylic acid group embedded within a saturated heterocyclic framework. The 2,2-dimethyl substitution enhances stability and modulates solubility, making it well-suited for use in synthetic intermediates requiring resistance to hydrolysis and facile incorporation into complex molecular architectures under standard conditions.
2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid serves as a versatile building block in medicinal and synthetic chemistry, offering enhanced stability due to its sterically protected tetrahydropyran core. The carboxylic acid functionality enables direct coupling or derivatization, while the 2,2-dimethyl substitution improves metabolic resistance and modulates lipophilicity. This scaffold facilitates efficient access to bioactive heterocycles and is well-suited for parallel synthesis campaigns requiring bench-stable, functionally tolerant intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: