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Structure of 530-91-6
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1,2,3,4-Tetrahydronaphthalen-2-ol features a hydroxyl group at the benzylic position of a partially saturated naphthalene core, enabling direct functionalization in synthetic routes. The molecule combines aromatic stability with enhanced solubility compared to fully aromatic analogs, facilitating use in medicinal chemistry and material science applications under standard bench conditions.
1,2,3,4-Tetrahydronaphthalen-2-ol serves as a versatile chiral building block in medicinal chemistry and natural product synthesis. Its hydroxyl group enables straightforward derivatization via esterification, etherification, or oxidation to the corresponding ketone. The tetralin core exhibits good bench stability and functional group tolerance, facilitating use in palladium-catalyzed coupling reactions and heterocycle formation. This scaffold is frequently employed in the construction of bioactive molecules due to its favorable lipophilic character and structural rigidity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P301+P310-P330-P501
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Lot numbers can be found on the outside label of a product: