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CS-W001157 4
Total: USD 88.00

2-Tetralone

  • CAS No. 530-93-8

  • Cat. No. CS-B0118
  • Purity≥97%
  • MDL No.MFCD00001727

*For research and further manufacturing use only, not for direct human use.

2-Tetralone|CS-B0118

Structure of 530-93-8

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General Information

  • CAS No. 530-93-8
  • Cat. No. CS-B0118
  • Purity ≥97%
  • MDL No. MFCD00001727
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O
  • Molecular Weight 146.19
  • Synonym(s) Beta-Tetralone
  • SMILES O=C1CC=2C=CC=CC2CC1

Description

2-Tetralone features a fused bicyclic structure with a ketone at the 2-position, offering high stability and compatibility in synthetic transformations. This aromatic ketone serves as a key scaffold in pharmaceutical intermediates and natural product synthesis, readily participating in electrophilic and nucleophilic reactions under standard conditions.

Application

2-Tetralone serves as a versatile building block in synthetic organic chemistry, enabling efficient access to fused bicyclic scaffolds. Its ketone functionality facilitates nucleophilic additions, reductions, and enolate-based transformations under standard conditions. The molecule exhibits good bench stability and compatibility with common protecting groups, making it well-suited for multi-step syntheses of heterocyclic compounds and bioactive intermediates.

Synthesis

  • Route1

    References

    • Da Silva, Ana C.; Piotrowski, Holger; Mayer, Peter; Polborn, Kurt; Severin, Kay European Journal of Inorganic Chemistry, 2001 , # 3 p. 685 - 691
  • Route2
    • 1a,2,3,7b-tetrahydronaphtho[1,2-b]oxirene|CS-1045950
      2461-34-9
    • ~92%
    • In-stock
      2-Tetralone|CS-B0118
      530-93-8

    References

    • Ranu, Brindaban C.; Chakraborty, Rupak Synthetic Communications, 1990 , vol. 20, # 12 p. 1751 - 1756
  • Route3

    References

    • Bulletin de la Societe Chimique de France, , vol. 2, # 5-6 p. 161 - 166

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.7444
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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